ビタミンDは骨生理学に含まれる重要な栄養素のひとつです。
写真左がノーマルな骨基質、右が骨粗鬆症。
『Anatomy & Physiotherapy』 より
Nutrition by Lesley Wassef-Birosik, PhD:
Osteoporosis is a common disease affecting the older population and is
associated with an increased risk of hip fractures. Hip fractures have
different severities (Garden I-IV and Kyle I-IV) and different
sites of fracture (intracapsular and extracapsular). Vitamin D is an
important nutrient involved in bone physiology.
The current
study analysed 324 patients with osteoporotic hip fractures over the age
of 65 and examine blood levels for vitamin D, calcium, potassium and
parathyroid. There was no difference in blood vitamin D levels between
the two sites of fractures.
Hypovitaminosis D was seen in
67% of patients. In addition, patients with a more severe hip fracture
had hypervitaminosis D and hyperparathyroidism compared to those with
less severe hip fractures. Interestingly, those that were treated with
vitamin D had less severe fractures.
Calcium levels were
similar suggesting that changes in bone remodeling are occurring to
ensure calcium levels are constant. Therefore, when treated patients
with osteoporotic hip fractures, vitamin D supplementation needs to be
considered. > From: Larrosa et al., Osteoporosis Int 23 (2012)
607-614. All Rights reserved to the International Osteoporosis
Foundation and the National Osteoporosis Foundation.
