ビタミンDは骨生理学に含まれる重要な栄養素のひとつです。
写真左がノーマルな骨基質、右が骨粗鬆症。
『Anatomy & Physiotherapy』 より
Nutrition by Lesley Wassef-Birosik, PhD:
Osteoporosis is a common disease affecting the older population and is associated with an increased risk of hip fractures. Hip fractures have different severities (Garden I-IV and Kyle I-IV) and different sites of fracture (intracapsular and extracapsular). Vitamin D is an important nutrient involved in bone physiology.
The current study analysed 324 patients with osteoporotic hip fractures over the age of 65 and examine blood levels for vitamin D, calcium, potassium and parathyroid. There was no difference in blood vitamin D levels between the two sites of fractures.
Hypovitaminosis D was seen in 67% of patients. In addition, patients with a more severe hip fracture had hypervitaminosis D and hyperparathyroidism compared to those with less severe hip fractures. Interestingly, those that were treated with vitamin D had less severe fractures.
Calcium levels were similar suggesting that changes in bone remodeling are occurring to ensure calcium levels are constant. Therefore, when treated patients with osteoporotic hip fractures, vitamin D supplementation needs to be considered. > From: Larrosa et al., Osteoporosis Int 23 (2012) 607-614. All Rights reserved to the International Osteoporosis Foundation and the National Osteoporosis Foundation.
Osteoporosis is a common disease affecting the older population and is associated with an increased risk of hip fractures. Hip fractures have different severities (Garden I-IV and Kyle I-IV) and different sites of fracture (intracapsular and extracapsular). Vitamin D is an important nutrient involved in bone physiology.
The current study analysed 324 patients with osteoporotic hip fractures over the age of 65 and examine blood levels for vitamin D, calcium, potassium and parathyroid. There was no difference in blood vitamin D levels between the two sites of fractures.
Hypovitaminosis D was seen in 67% of patients. In addition, patients with a more severe hip fracture had hypervitaminosis D and hyperparathyroidism compared to those with less severe hip fractures. Interestingly, those that were treated with vitamin D had less severe fractures.
Calcium levels were similar suggesting that changes in bone remodeling are occurring to ensure calcium levels are constant. Therefore, when treated patients with osteoporotic hip fractures, vitamin D supplementation needs to be considered. > From: Larrosa et al., Osteoporosis Int 23 (2012) 607-614. All Rights reserved to the International Osteoporosis Foundation and the National Osteoporosis Foundation.
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